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Nexium ® - Esomeprazole

Contents of this Article

  • Nexium Drug Interactions

Nexium - Esomeprazole and GERD

Esomeprazole - chemical name - Pronunciation - ess-oh-MEP-ra-zole
Nexium - brand name
The Purple Pill

Nexium (Esomeprazole) is available with a doctor's prescription and is commonly called by it's brand name, Nexium.

Nexium belongs to a group of drugs called proton pump inhibitors, or PPI's. They are:

  • Nexium - Esomeprazole
  • Prilosec - Omeprazole
  • Prevacid - Lansoprazole
  • Protonix - Pantoprazole
  • Aciphex - Rabeprazole

Chemically, Nexium is very similar to Prilosec (Omeprazole).

PPIs reduce the production of acid in the stomach and intestines by blocking the enzyme in the wall of the stomach that produces acid. Decreasing stomach acid can help ulcers to heal and reflux, or heartburn symptoms to subside.

Nexium is used to treat Gastroesophageal Reflux Disease (GERD), and Erosive Esophagitis, and other conditions involving excessive stomach acid production. The FDA also approved Nexium, in combination with two antibiotics, amoxicillin and clarithromycin, to treat * helicobacter pylori (H. pylori) infection, which is responsible for the majority of * gastric ulcers and * duodenal ulcers. Nexium may also be used to treat other conditions as determined by your doctor.

Gastroesophageal Reflux Disease (GERD)

Gastroesophageal Reflux Disease (GERD), pronounced - GAH-stroh-eh-SAW-fuh-JEE-ul REE-fluks duh-zeez, is the flow of the stomach's contents back up into the esophagus. Happens when the muscle between the esophagus and the stomach (the lower esophageal sphincter) is weak or relaxes when it shouldn't. May cause esophagitis. Also called esophageal reflux or reflux esophagitis. More about GERD

Esophagitis

Esophagitis, pronounced - eh-saw-fuh-JY-tis, is an irritation of the esophagus, pronounced - eh-SAW-fuh-gus, which is usually caused by acid that flows up from the stomach. The esophagus, also spelled oesophagus and also called gullet, is the organ that connects the mouth to the stomach. More about Esophagitis


Definitions For This Page - In Alphabetical Order

* Duodenal Ulcer
Pronounced - doo-AW-duh-nul UL-sur
Duodenal ulcer is an ulcer in the lining of the first part of the * small intestine (duodenum). The duodenum is right after your stomach.

* Gastric Ulcer
Pronounced - GAH-strik UL-sur
Gastric ulcer is an open sore in the lining of the stomach. Also called Stomach Ulcer.

* Helicobacter Pylori (H. pylori)
Pronounced - HELL-uh-koh-BAK-tur py-LOH-ree
Helicobacter Pylori (H. pylori) is a spiral shaped bacterium found in the stomach. H. pylori damages stomach and duodenal tissue, causing ulcers. Previously called Campylobacter pylori.

* Small Intestine
The small intestine is the organ where most digestion occurs. It measures about 22 feet and includes the duodenum, jejunum, and ileum. More about Small Intestine.


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The information discussed above is a general overview and does not include all the facts, or include everything there is to know about any medicine and/or products mentioned. Do not use any medicine and/or products without first talking to your doctor. Possible side effects of medications, other than those listed, may occur. Other brand names or generic forms of this medicine may also be available. If you have questions or concerns, or want more information, your doctor or pharmacist has the complete prescribing information about this medicine and possible drug interactions.